Among the new faces are batting duo Lhuan-dre Pretorius and Lesego Senokwane, both of whom have received their maiden call ups to the national setup.
They are joined in the squad by another first-timer in fast bowler Codi Yusuf.
The other uncapped players in the group are batter Dewald Brevis, the second-highest run-scorer in the domestic first-class competition this past season, and spinner Prenelan Subrayen, though both have previously toured with the Proteas senior side.
At just 19, left handed batter Pretorius enjoyed a breakout season in the domestic Cricket SA Four Day series.
He struck three hundreds in five first class games at an impressive average of 72.66, including a crucial 114 in the final that helped secure a hard-fought draw for the Titans against the Lions.
Senokwane also impressed with the bat, amassing 559 runs with two centuries to his name.
Both players also recently made their SA A debuts against West Indies A.
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