Ghazouani was leading with 49%, while his main rival, prominent anti-slavery activist Biram Dah Abeid, was at 22.68%, with around 6.49% of total votes counted, or 283 polling stations reporting out of 4 503 by 02:10 CAT.
Ghazouani, 67, a former top soldier who is widely expected to win, has pledged to boost investment to spur a commodities boom in the West African country of 5 million people, as it prepares to start producing natural gas.
"The last word belongs to the Mauritanian voters. I commit myself to respecting their choice," Ghazouani said after he voted in the capital early on Saturday.
Elected for a first term in 2019, Ghazouani is facing a field of six opponents, among them Abeid, who came second in 2019 with over 18% of the vote.
--Reuters--